該基因編碼一種屬于gata轉錄因子家族的蛋白質。該蛋白通過調節胎兒血紅蛋白向成人血紅蛋白的轉換，在紅系發育中發揮重要作用。該基因突變與x連鎖的紅細胞生成障礙性貧血和血小板減少癥有關。[由RefSeq提供，2008年7月]
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008]